When you fitted it to your bow did it come with a thin piece of rubber backing for in between the sight block and riser ?
If not then a sliver of old bicycle inner tube is surprisingly effective at reducing shock/vibration loosening sight adjustment screws.
Always worth getting a second set of eyes to check the bow over to see what is causing the vibration in the first place as a well tuned & set up bow won't normally vibrate very badly during a shot cycle.
Is it the main locking nut that holds the arm to the bracket on the riser that comes loose? If so its very common on "cheaper" sights.
Damping as much vibration out of your bow as possible will definitely help. Also worth looking at either adding some PTFE tape or light threadlock onto the main screw to give it a bit more bite and resist vibration loosening.